The Wright Lab

Highlight Publications

All Publications

Local plasticity underlies the reorganization of cortical circuit dynamics during motor learning. (2026) Wright, W.J.^†, Chen, E.C., Zhou, B., Wang, J., Liu, Z., Morales, B., & Komiyama, T.^† Current Biology,36;1-12. Read the paper

Refinement of Nucleus Accumbens Neuronal Dynamics During Cocaine Self-Administration Training. (2026) Jin, L.*, Qi, X.*, Liu, J., Wright, W.J., Schall, T.A., Li, K.L., Zeng, B., Wang, L., & Dong, Y.^† Journal of Neuroscience, 46(18). Read the paper

Distinct synaptic plasticity rules operate across dendritic compartments in vivo during learning. (2025) Wright, W.J.^†, Hedrick, N.G., & Komiyama, T.^† Science 388; 322-328. Read the paper

Temporal Dynamics of Nucleus Accumbens Neurons Launch Reward Seeking. (2024) Schall, T.A*., Li, K.L.*, Qi, X.*, Lee, B., Wright, W.J., Alpaugh, E.E., Zhao, R.J., Liu, J., Li, Q., Zeng, B., Wang, L., Huang, Y.H., Schlüter, O.M., Neslter, E.J., Nieh, E., & Dong, Y.^† Nature Communications, 15:9285; 1-15. Read the paper

Local and global predictors of synapse elimination during motor learning. (2024) Hedrick, NG*, Wright, WJ*, & Komiyama, T.^† Science Advances, 15;10(11). PMID: 38489360. Read the paper

CREB binding at the Zfp189 promoter within medium spiny neuron subtypes differentially regulates behavioral and physiological adaptations over the course of cocaine use. (2023) Teague, C*., Picone, J*., Wright, W.J., Browne, C., Silva, G., Futamura, R., Minier-Toribio, A., Estil, M., Ramakrishnan, A., Martinez-Rivera, F., Godino, A., Parise, E., Lorsch, Z., Hyun Kim, J., Shen, L., Neve, R., Dong, Y., Nestler, E., Hamilton, P.J.^† Biological Psychiatry, 93(6); 502-511. Read the paper

Silent synapses in addiction memory and beyond. (2021) Wright, W.J. & Dong, Y Journal of Neuroscience, 41(5); 9275-9285 (Review) Read the paper

Nucleus accumbens fast-spiking interneurons in motivational and addictive behaviors. (2021) Schall, T.*, Wright, W.J.*, & Dong, Y. Molecular Psychiatry, 26(1); 234-246. (Review) Read the paper

Psychostimulant-induced adaptations in nucleus accumbens glutamatergic transmission. (2020) Wright, W.J. & Dong Y. CSHL Perspectives in Medicine, (Invited review/book chapter) Read the paper

Silent synapses dictate cocaine memory destabilization and reconsolidation. (2020) Wright, W.J.*, Graziane, N.M.*, Neumann, P.A., Hamilton, P.J., Cates, H.M., Fuerst, L., Spenceley, A., Mackinnon-Booth, N., Iyer, K., Huang, Y.H., Shaham, Y., Schlüter, O.M., Nestler, E.J., & Dong, Y.^† Nature Neuroscience, 23(1); 32-46. Read the paper

Stress resilience is promoted by a Zfp 189-driven transcriptional network in prefrontal cortex. (2019) Lorsch, Z.S.*, Hamilton, P.J.*, Ramakrishnan, A., Parise, E.M., Salery, M., Wright, W.J., Lepack, A., Mews, P., Issler, O., McKenzie, A., Zhou, X., Parise, L.F., Pirpinias, S.T., Torres, I.O., Kronman, H.G., Montgomery, S., Loh, Y-H.E., Labonte, B., Conkey, A., Symonds, A.E. Neve, R., Turecki, G., Maze I., Dong, Y., Zhang, B., Shen, L., Bagot, R.C., & Nestler, E.J.^† Nature Neuroscience, 22(9); 1413-1423. Read the paper

Intrinsic excitability of cocaine-associated memories (2018) Wright, W.J. & Dong, Y. Neuropsychopharmacology, 43(4); 675-676. (Commentary) Read the paper

Tipping the scales towards addiction. (2017) Wright, W.J. & Dong, Y. Biological Psychiatry, 81(11); 903-904. (Commentary) Read the paper

A feedforward inhibitory circuit mediated by CB1-expression fast-spiking interneurons in the nucleus accumbens. (2017) Wright, W.J., Schlüter, O.M., & Dong, Y.^† Neuropsychopharmacology, 42(5); 1146-1156. Read the paper

NMDA receptors: “C”ing the culprits behind cocaine-induced metaplasticity. (2016) Wright, W.J. & Dong, Y. Biological Psychiatry, 80(9); 644-646. (Commentary) Read the paper

Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses. (2016) Graziane, N.M., Sun, S.*, Wright, W.J.*, Jang, D., Zheng, L., Huang, Y.H., Nestler, E.J., Wang, Y.T., Schlüter, O.M, & Dong, Y.^† Nature Neuroscience, 19(7); 915-925. Read the paper